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Medical electrical system. Guidelines for safe integration and operation of adaptive external-beam radiotherapy systems for real-time adaptive radiotherapy Ingestion-build-50790 travel and personal issue first1 Scope This document provides guidelines for safe integration and operation of an adaptive external beam radiotherapy system (AEBRS) for intra fractionally moving rigid target volumes, where required equipment can be sourced from one or several manufacturers. In particular it addresses guidelines to help ensure safe integration and operation for the patient, operator, other persons and sensitive devices in the vicinity. In this document, the word