The Binding of Isaac: Four Souls STRATEGY 2-6 players start the game

2-6 players start the game by choosing (in reverse player order) a starting location for one of their three city pieces

and you may play one or more adventures in a game session

and create the most prosperous empire

Being cursed forces a player to take the Cursed card and roll the black die along with the rest of his dice pool

The Binding of Isaac: Four Souls STRATEGY 2-6 players start the gameThe official Binding of Isaac multiplayer card game, about sacrifice, betrayal and hoarding. 2 4 players take turns playing loot cards and using items to kill monsters that yield more items, loot, and sometimes souls. The first player to end their turn with 4 souls is the winner. Cooperation, barter, and betrayal is encouraged.